"Poignantly" is a word in ENGLISH

Causing, or fitted to cause, pain or distress to the mind; calamitous; poignant.

A picking of heart; poignant grief proceeding from a sense of guilt or consciousness of causing pain; the sting of …

To make more poignant or affecting; to increase in degree; as, to deepen grief or sorrow.

To feel or to express deep and poignant grief for; to bewail; to lament; to mourn; to sorrow over.

mapainumúron - (H) Abstinent, abstemious, frugal, self-denying, temperate or moderate in eating and drinking. (úmud). mapa-ít, Bitter, acrid, biting, piquant, …

masakít - Sick, ill, infirm, ailing, unwell, poorly, sore, out of sorts, seedy, painful, aching, poignant, smarting, hurting, excruciating; sharp, …

pa-ít - Bitterness; pain, grief; to be or become bitter; harsh, acrid, biting, pungent, sharp, unpalatable; be hard to bear, …

The quality or state of being poignant; as, the poignancy of satire; the poignancy of grief.

Pricking; piercing; sharp; pungent.

Fig.: Pointed; keen; satirical.

Sharply painful; penetrating; poignant; severe; caustic; stinging.

To make poignant; to give zest, flavor or interest to; to set off; to vary and render attractive.

Keen; severe; poignant; as, smart pain.